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Taxis are readily available outside the terminal. An airport bus is available that connects to the underground system. There is also a jet express airport shuttle serving central Berlin. Berlin's integrated public transport system (the BVG) is the best way to get about. One ticket allows travel on all trains, trams, buses and ferries.
From the airport take the exit for Kurfurstendamm. Turn left onto Kurfurstendamm in the direction of Zentrum. Keep driving along Kurfurstendamm until the intersection of Kurfurstendamm/Uhlandstrasse, taking the left turn at this point. Turn left again into Grolmanstrasse, where the hotel is on the left.