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From Quincy Regional Airport:
Approximate distance to the hotel is 28 miles.
Go south on CR-1700 E. toward N. 1200th Ave/IL-104 W.
Turn right on N. 1200th Ave/IL-104 W.
Merge on I-172 S. via the ramp on the left.
Merge on I-72 W/US-36 W. via Exit 4C toward Hannibal.
Take Exit 157 toward Louisiana/Downtown Hannibal.
Turn left on US-36 BR/US-61 BR/Mark Twain Ave/MO-79.